Game Boy Tile Designer
From GbdevWiki
Game Boy Tile Designer, by Harry Mulder, is a graphical sprite editing application.
It exports to various assembly filetypes, binary, and a C array.
A updated version with some fixes and improvements is available from the GBDK-2020 project:
We're storing a copy of the last original version: http://gbdev.gg8.se/files/tools/
The original website, for historical purposes is here: http://www.devrs.com/gb/hmgd/gbtd.html.